Erratum to: Test-retest analysis of a non-invasive method of quantifying [(11)C]-PBR28 binding in Alzheimer's disease

نویسندگان

  • Akshay Nair
  • Mattia Veronese
  • Xiaohui Xu
  • Charles Curtis
  • Federico Turkheimer
  • Robert Howard
  • Suzanne Reeves
چکیده

Erratum Following publication of the original article [1] the authors contacted the team with the request that some additional information be added to the article. Please see below for details: Additional Table: absolute variability Variability (VAR) presented in the main article represents mean variability between test and retest, not absolute variability as stated. The authors would like to apologise for this error. The absolute variability is presented in the table below has been calculated in the following manner:

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Test-retest analysis of a non-invasive method of quantifying [11C]-PBR28 binding in Alzheimer’s disease

PURPOSE In order to maximise the utility of [(11)C]-PBR28 for use in longitudinal studies and clinical trials in Alzheimer's disease (AD), there is a need to develop non-invasive metrics of tracer binding that do not require arterial cannulation. Recent work has suggested that standardised uptake value (SUV)-based methods may be sensitive to changes in translocator protein (TSPO) levels associa...

متن کامل

Test-retest variability of adenosine A2A binding in the human brain with 11C-TMSX and PET

BACKGROUND The goal of the present study was to evaluate the reproducibility of cerebral adenosine A2A receptor (A2AR) quantification using (11)C-TMSX and PET in a test-retest study. METHODS Five healthy volunteers were studied twice. The test-retest variability was assessed for distribution volume (V T) and binding potential relative to non-displaceable uptake (BPND) based on either metaboli...

متن کامل

پایایی، روایی و تحلیل عاملی پرسش‌نامه بی‌قراری کوهن- منسفیلد (CMAI)

Objectives: In order to investigate the effectiveness of pharmacological and non-pharmacological treatment methods for decreasing agitation in diseases like dementia, a proper scale like Cohen-Mansfield Agitation Inventory (CMAI) is needed. The aim of the present study was to evaluate the psychometric properties of the CMAI. Method: The sample consisted of 100 caregivers of patients with Alzhei...

متن کامل

Endotoxin-induced systemic inflammation activates microglia: [11C]PBR28 positron emission tomography in nonhuman primates

UNLABELLED Microglia play an essential role in many brain diseases. Microglia are activated by local tissue damage or inflammation, but systemic inflammation can also activate microglia. An important clinical question is whether the effects of systemic inflammation on microglia mediate the deleterious effects of systemic inflammation in diseases such as Alzheimer's dementia, multiple sclerosis,...

متن کامل

Cocaine abuse in humans is not associated with increased microglial activation: an 18-kDa translocator protein positron emission tomography imaging study with [11C]PBR28.

Basic science investigations have consistently shown that repeated exposure to psychostimulant drugs, such as cocaine, activate the immune response and lead to inflammatory changes in the brain. No previous in vivo studies have confirmed this observation in chronic cocaine-abusing humans. To test this hypothesis, we used positron emission tomography imaging to measure the binding of [(11)C]PBR2...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 7  شماره 

صفحات  -

تاریخ انتشار 2017